Selected Publications in Refinement and Applications of Continuum Solvation Models

Bao, X., X. Liu, R. Dou, S. Xu, D. Liu, J. Luo, X. Gong, C. F. Wong and B. Zhou (2023). "How are N-methylcarbamates encapsulated by β-cyclodextrin: insight into the binding mechanism." Physical Chemistry Chemical Physics 25(20): 13923-13932.
Chen, K., R. Ye, X. Liu, C. F. Wong, S. Xu, J. Luo, X. Gong and B. Zhou (2021). "Why 2,6-di-methyl-β-cyclodextrin can encapsulate OH-substituted naphthalenes better than β-cyclodextrin: Binding pose, non-covalent interaction and solvent effect." Computational and Theoretical Chemistry 1206.
Dou, R., K. Chen, G. Chi, J. Luo, C. F. Wong and B. Zhou (2021). "Why heptakis(2,3-di-O-acetyl)-β-cyclodextrin can separate terbutaline enantiomers better than β-cyclodextrin: nonbonding and hydrophobic interactions." Journal of Inclusion Phenomena and Macrocyclic Chemistry 100(3-4): 189-195.
Ye, R., X. Nie, C. F. Wong, X. Gong, Y. A. Wang, T. Heine and B. Zhou (2016). "Variable van der Waals radii derived from a hybrid Gaussian charge distribution model for continuum-solvent electrostatic calculations." Zeitschrift fur Physikalische Chemie 230(5-7): 681-701.
Ye, R., X. Nie, Y. Zhou, C. F. Wong, X. Gong, W. Jiang, W. Tang, Y. A. Wang, T. Heine and B. Zhou (2016). "Exploring host-guest complexation mechanisms by a molecular dynamics/quantum mechanics/continuum solvent model approach." Chemical Physics Letters 648: 170-177.
Shi, J., Q. Lu, M. Zhang, M. Wang, C. F. Wong and J. Liu (2010). "Supplementing the PBSA approach with quantum mechanics to study the binding between CDK2 and N2-substituted O6-cyclohexylmethoxyguanine inhibitors." J. Theor. Comput. Chem. 9: 543-559.
Zhou, B., M. Agarwal and C. F. Wong (2008). "Variable Atomic Radii for Continuum-Solvent Electrostatics Calculation." J Chem Phys 129: 014509.
Wang, M. L., C. F. Wong, J. Liu and P. Zhang (2007). "Efficient quantum mechanical calculation of solvation energies based on density functional theory, numerical atomic orbitals and Poisson-Boltzmann equation." Chemical Physics Letters 442: 464-467.
Wang, M. L. and C. F. Wong (2007). "Rank-ordering protein-ligand binding affinity by a quantum mechanics/molecular mechanics/Poisson-Boltzmann-surface area model." Journal of Chemical Physics 126(2): 026101.
Wang, M. L. and C. F. Wong (2006). "Calculation of solvation free energy from quantum mechanical charge density and continuum dielectric theory." Journal of Physical Chemistry A 110(14): 4873-4879.
Sims, P. A., C. F. Wong, D. Vuga, J. A. McCammon and B. M. Sefton (2005). "Relative contributions of desolvation, inter- and intramolecular interactions to binding affinity in protein kinase systems." J Comput Chem 26(7): 668-681.
Sims, P., C. Wong and J. McCammon (2004). "Charge optimization of the interface between protein kinases and their ligands." JOURNAL OF COMPUTATIONAL CHEMISTRY 25(11): 1416-1429.
Sims, P., C. F. Wong and J. A. McCammon (2003). "A Computational Model of Binding Thermodynamics: The Design of CDK2 Inhibitors." J Med Chem 46(15): 3314-3325.
Toendel, K., C. F. Wong and J. A. McCammon (2003). "Computational Analysis of the Interactions between the Angiogenesis Inhibitor PD173074 and Fibroblast Growth Factor Receptor 1." J Theor Comput Chem 2(1): 43-56.
Gidofalvi, G., C. F. Wong and J. A. McCammon (2002). "Entropy Loss of Hydroxyl Groups of Balanol upon Binding to Protein Kinase A." J. Chem. Ed. 79(9): 1122-1126.
Gould, C. and C. F. Wong (2002). "Designing specific protein kinase inhibitors: insights from computer simulations and comparative sequence/structure analysis." Pharmacology and Therapeutics 93(2-3): 169-178.
Wong, C. F., P. H. Hünenberger, P. Akamine, N. Narayana, T. Diller, J. A. McCammon, S. Taylor and N. H. Xuong (2001). "Computational analysis of PKA-balanol interactions." Journal of Medicinal Chemistry 44(10): 1530-1539.