Sharlee Climer, Ph.D.

Office Hours:

Tue: 3:30 PM - 5:15 PM
Thu: 3:30 PM - 4:45 PM

In Person (319 ESH) or via Zoom.

Additonal Times available upon request. 

Main Research Interests

• Computational Biology
• Combinatorial Optimization
• Clustering and Network Modeling
• Mathematical Linear Programming

Selected Research Involvement

• Identification of analyte and genetic patterns associated with complex traits, including COVID-19 and Alzheimer’s disease
• Optimal combinatorial associations for complex traits, including COVID-19 and Alzheimer’s disease
• Optimization of objective functions for clustering algorithms
• Data visualization using heatmaps

External Grants

• “A Multipronged Interrogation of Large-Scale Omics Data to Reveal COVID-19 Pathways”, NIH, 2020-2021 (PI)
• “Using quantitative traits to identify novel genes for Alzheimer’s disease and other complex traits”, NIH, 2015-2020 (PI)
• National Human Genome Research Institute (NHGRI) LRP awards, 2015-present (PI)
• “Ecological genomics: analysis of gene expression underlying parallel habitat adaptation in distinct salamander species”, Deutsch-Israel Project grant, 2013-2017 (Consultant)
• “A Novel Co-expression Network Approach that is Robust to Genetic Heterogeneity”, NIH, 2012-2016 (Investigator)