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Sharlee Climer

Associate Professor
Ph.D. in Computer Science, Washington University in
St. Louis, 2006. 

Email: climer@umsl.edu

 Phone: (314) 516-4958

Fax: (314) 516- 5400

Office Hours:

Tue: 3:30 PM - 5:15 PM

Thu: 3:30 PM - 4:45 PM

In Person (319 ESH) or via Zoom. 

 https://umsystem.zoom.us/my/climer

 

Additonal Times available upon request. 

 

Publications

Personal Webpage

Main Research Interests

  • Computational Biology
  • Combinatorial Optimization
  • Clustering and Network Modeling
  • Mathematical Linear Programming

Selected Research Involvement

  • Identification of analyte and genetic patterns associated with complex traits, including COVID-19 and Alzheimer’s disease
  • Optimal combinatorial associations for complex traits, including COVID-19 and Alzheimer’s disease
  • Optimization of objective functions for clustering algorithms
  • Data visualization using heatmaps

External Grants

  • “A Multipronged Interrogation of Large-Scale Omics Data to Reveal COVID-19 Pathways”, NIH, 2020-2021 (PI)
  • “Using quantitative traits to identify novel genes for Alzheimer’s disease and other complex traits”, NIH, 2015-2020 (PI)
  • National Human Genome Research Institute (NHGRI) LRP awards, 2015-present (PI)
  • “Ecological genomics: analysis of gene expression underlying parallel habitat adaptation in distinct salamander species”, Deutsch-Israel Project grant, 2013-2017 (Consultant)
  • “A Novel Co-expression Network Approach that is Robust to Genetic Heterogeneity”, NIH, 2012-2016 (Investigator)