High Field NMR Facility

The UMSL High Resolution NMR Facility is located in the Department of Chemistry and Biochemistry on the second floor of the new Science Learning Center  (SLB 216) and houses three NMR spectrometers: a Agilent DD2 600, a Bruker Avance 300 and a Varian Unity Plus 300.  While these instruments are primarily for the use of the faculty, postdoctoral, and students in the Department of Chemistry and Biochemistry, other users (corporate other universities, and organizations) are welcome. The facility staff will provide NMR services as needed. For more information please contact to Dr. Rensheng Luo at (314) 516-5330.

 
Agilent DD2 600 MHz NMR Spectrometer

With support from NSF MRI-R2 grant (0959360), an Agilent DD2 600 MHz NMR spectrometer was purchased and installed in early 2012. This spectrometer is operated by a Linux PC with VnmrJ 4.1 software. 

Two probes are available: a 5-mm three channel inverse gradient broadband and a 5-mm gradient broadband, each of which is capable of variable temperature experiments (-80 to +130^oC). This spectrometer is a research-oriented instrument and primarily used to investigate the structures and dynamics of macromolecules and complex molecular systems as well as implement new NMR experiments for users at different areas. 

The instrument specifications include:

•  The Agilent premium COMPACT magnet (54mm bore)
•  Dell PC with Red Hat Linux
•  ¹H-¹⁹F/¹⁵N-³¹P, ¹⁵N/¹³C 5mm PFG triple OneNMR probe
•  ¹H-¹⁹F/¹⁵N-³¹P 5mm PFG autoX indirect detection probe
•  ProTune accessory
•  Variable temperature capability (-80^oC to +130^oC)

Bruker Avance 300MHz NMR Spectrometer

The Avance 300 spectrometer is equipped with a four-nucleus probe (¹H, ¹³C, ¹⁹F, and ³¹P) with z-gradients. An additional 5 mm switchable broadband probe tunable for ¹H, ¹⁹F, ¹⁵N ³¹P is also available. The instrument is used for routine walk-in use for monitoring reactions and checking the purity of samples, but it is also used for longer run experiments such as 1D ¹³C and routine 2D experiments: HMQC, HSQC, and HMBC in the evening and weekends. 

 
Varian Unity Plus 300 MHz NMR

The Varian Unity Plus 300 has a wide bore Oxford superconducting magnet to facilitate solid state NMR experiments, two radiofrequency channels and is capable of broadband detection. It is used primarily for detection of heteronuclei such as ¹¹B, ¹³C, ³¹P, ¹¹⁹Sn, and ¹⁹⁵Pt. It has four probes: two 5 mm switchable broadband probes with boron-free glass insert, a 5 mm switchable inverse broadband probe, and a 7 mm magic angle probe for CP-MAS experiments.