ORTHOKERATOLOGY

Objectives of this lecture:

1.      To understand the applications and design/fitting principles in orthokeratology

I. DEFINITION

A method - utilizing contact lenses - for correction of refractive error, primarily myopia, by reshaping the curvature of the cornea. The treatment consists of fitting a series of specially designed, progressively flatter rigid contact lenses which are intended to graduallt remold the cornea.

II. CHARACTERISTICS

  1. Average Cost: $1000 - $1500
  2. Length of Program: Traditionally = 1 year
    Accelerated: 6 months
  3. Average Maximum Change:
    3D less myopia
    2D less hyperopia

III. PATIENT SELECTION

1. Ideal Patient
        • High Motivation
        • Availability
        • Can Afford Costs
        • Low Myopes
        • Low Cylinder
2. Occupational Applications
        • Airline Pilots
        • Military
        • Firemen/Police
        • Bus Drivers

IV. ORTHOKERATOLOGY VERSUS REFRACTIVE SURGERY

1. Benefits
        • Non-Invasive
        • Side Effects Not Permanent
2. Disadvantages
        • Temporary Change
        • Unpredictable

V. BENEFITS OF CORNEAL TOPOGRAPHY IN ORTHOKERATOLOGY

1. Selecting Good Candidates
        • No irregular corneas
        • No undetected pathologies
2. Orthokeratology Lens Selection
        • Based on central corneal curvature and eccentricity
3. Follow Corneal Changes with Time
4. Correlate Vision with Lens Effects on Cornea
5. Corneal Topography Change as a Predictor
        • Rate of flattening = eccentricity
        • In orthokeratology the central cornea flattens and the peripheral cornea steepens
        • Eccentricity gradually approaches zero (from .4 - .6)
        • Mountford Equation: y = .20x
            y = eccentricity; x = refractive change (in D)
            If y = .5; x = 2.5D
            If y = .4; x = 2D
            If y = .6; x = 3D

VI. FITTING

1. Traditional Philosophies
        • Much flatter than "K"
        • Variability and WTR cylinder induced
        • 1 - 3D change over 1 year
2. Accelerated Orthokeratology
        • Orthokeratology lenses with secondary curve steeper than base curve (i.e., reverse geometry design)
        • These lenses accelerate the orthokeratology effect; typically achieve same effect in 3 months as 1 year of
           traditional orthokeratology
        • Reverse Geometry lenses are typically fit 1.5 - 2D flatter than "K". They achieve 4 - 5mm central bearing with
           2 - 3mm of mid-peripheral pooling. Good centration with limited movement is the goal. These lenses often have
           a 6 - 7mm OZD.
        • The OK Series from Contex     Series OZD SCR Use
            OK-2 6.5 2D Retainer
            OK-3 6.0 3D Starting Lens   
            OK-4 6.0 2D Improve Centration of OK-2
            OK-5P 6.5 3D BD prism to lower lens
            OK-6 6.5 3D For large pupils
            OK-7 7.0 3D For large pupils
        • Any reverse geometry lens can be successful including so-called RK lenses (Plateau)

Lens Changes:
        • With reverse geometry designs, refractive changes occur within a few days
        • Subsequent BCR should be 0.50D flatter than previous lens
        • When spherical corneal contour is present, no change indicated

VII. RETAINER LENS WEAR

1. Typically last OK lens or a slightly flatter one; worn a few hours/day
2. Overnight Wear
        • High Dk lens worn EW
        • Eliminates problems with irritants, wind and dust

VIII. ADVERSE EFFECTS

1. Increased Corneal Astigmatism
        • Less pressure on vertical meridian
        • Greater with radically flat BCR
        • Lens decentration
2. Peripheral Corneal Distortion
        • Too flat too soon
        • Flat peripheral cornea
3. Decreased Quality of Vision
        • Haziness or "watery" vision
        • Due to corneal changes/induced astigmatism
4. Visual Problems at Near
        • Hyperactivity of accommodative system
5. Regression Toward Pre-Fit Level
        Berkeley Orthokeratology Study (Polse)
        • 80 treatment subjects, 40 control
        • three phases
        • Evaluation of safety & efficacy
        • Results:
            a. OK can reduce myopia by 1D which can be clinically significant
            b. Change is temporary; when CL wear is reduced to 4 hours; 45% of RE change is
                 lost.   Complete return to baseline did not occur.
            c. Vision is variable without CLs
            d. Safety acceptable although monitoring important

IX. SUMMARY

  1. Orthokeratology is experiencing a rebirth as a refractive surgery alternative.
  2. Orthokeratology produces the desired changes in certain individuals but consider the risk-to-benefit ratio.
  3. It is important to frequently monitor the lens-to-cornea fitting relationship, corneal integrity and topography.
  4. A greater chance of success is present with lower RE's and greater shape factors/eccentricities.
  5. Regression studies show that the change is temporary. If CL wear is d/c, vision becomes variable.
  6. Greater promise and predictability due to use of reverse geometry lenses in combination with monitoring with corneal topography is present