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Ph.D. in Computer Science, University of Missouri-Columbia, 2017
B.E. in Computer Engineering, Tribhuvan University, Kathmandu, Nepal, 2009
Office: 312 ESH
Phone: (314) 516-7393
Fax: (314) 516-5400Office Hours: R 6:45 PM – 9:45 PM
By Appointment Only
During this COVID-19 outbreak, I may not be present at my office during my office hours. Please email me. If needed, we can set up a meeting via Zoom or telephone.
Main Research Interests
- Deep learning and Bioinformatics
- Protein inter-residue distance prediction
- Deep learning for improving human health
Selected Research Involvements
- Development of various tools for modeling 3D structures of proteins and chromosomes, supported by NSF and NIH.
- Development of deep learning-based tools and methods for solving various problems in the field of protein structure prediction, supported by NSF, NIH, NVIDIA, and Google.
- Artificial intelligence methods Autonomous Environmental Monitoring and Management, supported by NASA.
- Machine learning methods development for collaborators in various departments at UMSL.
- $163,535, National Science Foundation CISE CRII, 2020 (PI).
- $6,450, UMSL Research Award, 2019 (PI).
- $5,415, UMSL Research Award, 2018 (PI).
- Adhikari, B. A fully open-source framework for deep learning protein real-valued distances. Nature Scientific Reports10,2045–2322 (2020).
- Adhikari, B. DEEPCON: protein contact prediction using dilated convolutional neural networks with dropout. Bioinformatics 36, 470–477 (2020).
- Adhikari, B., Hou, J. & Cheng, J. DNCON2: improved protein contact prediction using two-level deep convolutional neural networks. Bioinformatics 34, 1466–1472 (2018).
- Adhikari, B., Trieu, T. & Cheng, J. Chromosome3D: reconstructing three-dimensional chromosomal structures from Hi-C interaction frequency data using distance geometry simulated annealing. BMC genomics 17, 886 (2016).
- Adhikari, B., Bhattacharya, D., Cao, R. & Cheng, J. CONFOLD: residue-residue contact-guided ab initio protein folding. Proteins: Structure, Function, and Bioinformatics 83, 1436–1449 (2015).